Being afraid of something can cause us to make the exact wrong decision because fear is bad advice. In business, it might be a sign that you should do the opposite of what we’re afraid of.
For example, if you don’t want to tell your investors that things aren’t going well because you are afraid you will lose their trust, you probably should tell them and it will gain their trust.
(This doesn’t apply to physical danger, you should probably trust your fear of, say, a mountain lion)
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It’s obvious that living life without fear is a good thing, but what about life without hope?